1. | Ministry of Defence and National Security | The Rt. Hon. Samuel Ntsokoane Matekane |
2. | Deputy Prime Minister and Minister of Parliamentary Affairs | Hon. Justice Nthomeng Majara MP |
3. | Ministry of Health | Hon. Selibe Mochoboroane MP |
4. | Ministry of Education and Training | Hon. Dr Ntoi Rapapa MP |
5. | Ministry of Information, Communications, Science, Technology and Innovation | Hon. Nthati Moorosi MP |
6. | Ministry of Finance and Development Planning | Hon. Dr Retšelisitsoe Matlanyane MP |
7. | Ministry of Trade, Industry and Small Business | Hon. Mokhethi Shelile MP |
8. | Ministry of Local Government, Chieftainship, Home Affairs and Police | Hon. Lebona Lephema MP |
9. | Ministry of Foreign Affairs and International Relations | Hon. Mpotjoane Lejone MP |
10. | Ministry of Agriculture, Food Security and Nutrition | Hon. Thabo Mofosi MP |
11. | Ministry of Natural Resources | Hon. Mohlomi Moleko MP |
12. | Ministry of Gender, Youth, and Social Development | Hon. Pitso Lesaoana MP |
13. | Ministry of Public Works and Transport | Hon. Neo Matjato Moteane |
14. | Ministry of Labour and Employment | Hon. Ts’eliso Mokhosi |
15. | Minister in the Prime Minister’s Office | Hon. Limpho Tau Senator |
16. | Ministry of Energy | Hon. Prof. Nqosa Mahao |
17. | Ministry of Tourism, Sports, Arts and Culture | Hon. Motlatsi Maqelepo |
18. | Ministry of Public Service | Hon. Mputhi Mputhi |
19. | Ministry of Environment and Forestry | Hon. Letsema Adonts’i |
20. | Ministry of Law and Justice | Hon. Richard Ramoeletsi |